PostDoc-Structural Biology-Birkbeck, University of London, UK (London)
Location: London, United Kingdom
Birkbeck, University of London (formerly Birkbeck College, informally Birkbeck), is a public research university located in Bloomsbury, London, United Kingdom. Established in 1823, Birkbeck specialises in evening higher education and is a constituent college of the federal University of London.
It offers offering over 200 full-time undergraduate and postgraduate programmes that can be studied either part-time or full-time, though nearly all teaching is in the evening. It also admits full-time (as well as part-time) students for PhDs. Its staff members have excellent research reputations in subjects such as Crystallography, Economics, English, History, History of Art, Law, Linguistics, Philosophy, Psychology, Spanish, Statistics, and Science. It also offers many continuing education courses leading to certificates and diplomas, foundation degrees, and short courses. Research at Birkbeck in 11 subject areas is rated as ‘internationally excellent’ and ‘world leading’ while over 90 percent of Birkbeck academics are research-active. The Queen’s Anniversary Prize for excellence in higher education research was awarded in 2006.
Birkbeck counts four Nobel prize winners and a British Prime Minister among its former students and faculty. Birkbeck, being part of the University of London, shares the University’s academic standards and awards University of London degrees. In common with the other University of London colleges, Birkbeck has also secured its own independent degree awarding powers, which were confirmed by the Privy Council in July 2012. The quality of degrees awarded by Birkbeck was confirmed by the UK Quality Assurance Agency following institutional audits in 2005 and 2010.
We are seeking a motivated and creative Post Doctoral Researcher (Level 2) to dissect the molecular properties of malaria kinesins required for parasite replication using cryo-electron microscopy. This work is funded by Biotechnology and Biological Sciences Research Council (BBSRC) and will be performed as part of the research team led by Prof Carolyn Moores.
Kinesins are a large superfamily of ATP-driven, microtubule-based motors. They perform a variety of essential functions in eukaryotic replication, but their roles in malaria replication are poorly understood. The goal of this project is to apply state-of-the-art cryo-EM methods to visualise the mechanistic basis of malaria kinesin function. We will combine these structural studies with biophysical characterisation to evaluate their motile properties. This project will also be performed in close collaboration with the group of Professor Rita Tewari (University of Nottingham, //www.tewarilab.co.uk), an expert in Plasmodium cell biology, providing crucial in vivo context for our in vitro studies. The appointee will be a member of a team working on regulatory mechanisms of cytoskeleton dynamics (//people.cryst.bbk.ac.uk/~ubcg62d/) and will interact with members of the Birkbeck Electron Microscopy group (//people.cryst.bbk.ac.uk/~ubcg16z/empage.html). This project presents unique opportunities to study kinesins from evolutionarily divergent organisms, thereby illuminating novel motor properties and regulatory mechanisms in cell division.
Birkbeck College, University of London (www.bbk.ac.uk) is a world-class research and teaching institution. The Department of Biological Sciences is a multidisciplinary department and is part of the Institute of Structural and Molecular Biology (www.ismb.lon.ac.uk), a centre of excellence jointly with the Department of Structural & Molecular Biology at UCL. The Institute provides a world-class biomedical science research environment.
Applicants should have a PhD in structural biology, biochemistry or a related area, and have relevant research publications.
Grade 7 of the College’s London Pay Scale which is £36,150 rising to £41,318 per annum.
This is a full-time and fixed term position for up 35 months. The salary quoted above is on the College’s London Pay Scale and includes a consolidated Weighting/Allowance which applies only to staff whose normal contractual place of work is in the Greater London area. The initial salary will be dependent on the skills and experience of the successful applicant. The appointment may be subject to a probationary period of twelve months. Birkbeck also provides a generous final salary pension scheme, 31 days paid leave, flexible working arrangements and other great benefits.
How to apply
The closing date for completed applications is midnight on July 31st, 2016.Interviews will be held on a date yet to be confirmed (mid-August).Informal enquiries can be made to Professor Carolyn Moores
Email: firstname.lastname@example.org Telephone: 0207 631 6858.
To apply for this post please visit: www.bbk.ac.uk/jobs quoting the reference number, 11905