Postdoc- Microbial Genetics/molecular biology, and/biochemistry, Oregon Health & Science University, USA (Oregon)
Location: Portland, Oregon, United States
The Oregon Health & Science University School of Dentistry is the dental school of Oregon Health & Science University. It is located in the city of Portland, Oregon, United States. It is the only dental school in Oregon. Oregon Health & Science University School of Dentistry is a part of Oregon Health & Science University. The school was established in 1899 when the Oregon College of Dentistry merged with the Tacoma College of Dental Surgery to create the North Pacific Dental College in Portland.After being renamed as North Pacific College, that school merged into the then University of Oregon Medical School in 1945.
S. mutans is one of the primary species in the oral flora responsible for triggering caries-related dysbiosis, which ultimately results in tooth decay if left untreated. Our laboratory studies S. mutans genetics as a model system to better understand gene regulatory mechanisms important for triggering dysbiosis among the human flora as well as novel approaches to selectively inhibit particular species of bacteria living in mixed communities. A second research emphasis in the lab uses Anginosus Group streptococci to understand the mechanisms of polymicrobial synergy in dysbiotic diseases of the human mucosae.
Current projects include: 1) characterize pleiotropic, post-transcriptional gene regulatory mechanisms, especially those related to environmental stress, and 2) determine the mechanistic basis for polymicrobial synergy in mixed species infection models.
Candidates should be highly self-motivated and possess a strong background in microbial genetics, molecular biology, and/or biochemistry.
Typical duties of this position include:
genetic mutation construction, gene expression analysis, protein expression/purification, EMSA, Co-IP, northern blotting, western blotting, and fluorescence microscopy.
- PhD in related field of science, evidence of extensive experience with current genetic, molecular biology, and/or biochemistry techniques
- Excellent verbal and written communication skills
- Ability to work independently and as part of a team
- Microbial ecology and/or bacteriology experience
- Experience working with RNA
- Protein purification
- Strong background in gene regulation and/or post-translational regulation
- Experience handling mice
- Ability to contribute to the writing of scientific papers and/or grants
OHSU is an equal opportunity, affirmative action institution. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of disability or protected veteran status. Applicants with disabilities can request reasonable accommodation by contacting the Affirmative Action and Equal Opportunity Department at 503-494-5148.
How to apply
Apply online at //www.ohsu.edu.edu/xd/about/services/human-resources/ and search by keyword IRC53075