Postdoc-Host-Pathogen interaction-Francis Crick Institute, United Kingdom (London)
Location: London, United Kingdom
Description: We are offering a 4-year Postdoctoral Fellowship in the laboratory of Dr Moritz Treeck at the Francis Crick Institute. We are a diverse group trying to understand signalling pathways that intracellular parasites use to successfully infect a host. We use a variety of techniques, ranging from cell-biology and biochemistry to state-of-the-art quantitative mass-spectrometry. For a description of ongoing projects in the lab visit: www.treecklab.org. We are looking for a highly motivated candidate to investigate the function of kinases that the malaria parasite Plasmodium falciparum secretes into the host cell. A background in biochemistry or genetics is a prerequisite.
The Francis Crick Institute (the Crick) is a registered charity whose purpose is to conduct biomedical research into all aspects of human health and disease. Dedicated to research excellence, the institute will be a world-leading centre of biomedical research and innovation.
PROJECT SCOPE/ DESCRIPTION
The postdoctoral researcher will investigate the function of conditional kinase KO lines to identify their contribution to remodelling of the human erythrocyte by the malaria parasite. State of the art genetic tools, cell biological assays and quantitative mass-spectrometry will be used to characterize cell lines defective in exported parasite kinases. This work requires the ability to establish various cell biological and biochemical assays as well as careful maintenance of malaria parasite cultures. A strong background in biochemistry, genetics, molecular biology, cell biology or a related field is essential.
PLEASE NOTE: ALL OFFERS OF EMPLOYMENT ARE SUBJECT TO SUCCESSFUL SECURITY SCREENING AND CONTINUOUS ELIGIBILITY TO WORK IN THE UNITED KINGDOM.
How to apply: If you are interested in applying for this role, please apply via our website .
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